Table of Contents
Common Questions
Chat with CodyMD
Cody's Chat with Patient
Cody's AI Summary
Top 3 AI Diagnosis List
Review by Dr Albert DiPiero
Dr. DiPiero Video Guide to this Case Study
Resource Center
Testimonials
Share this Case Study
Meet your host

Albert DiPiero, MD MPH FACP
I am a co-founder and the Chief Medical Officer at CodyMD and your host for this edition of Cody Grand Rounds. I have been a practicing physician and faculty member at medical schools for over 26 years.
About The AI Doctor Case Study
CodyMD is a partnership between Human Doctors and AI Doctors. Cody is an AI Doctor who helps thousands of people every day. At each Cody Grand Rounds, I select a real case and review it with Cody, the AI Doctor.
Each case is based on a real patient but has been modified to maintain privacy and to emphasize certain teaching points.
What causes fatigue and low energy?
How does anxiety affect sleep?
What are symptoms of iron deficiency anemia (IDA)?
How can diet impact energy levels?
What is hypothyroidism?
How do heavy periods affect health?
What steps can be taken to improve fatigue?
Can AI doctors diagnose the causes of fatigue and low energy?
What is the role of AI symptom checker?
Click the button below to initiate a conversation with CodyMD, your AI Doctor.
Below is a conversation transcript between the patient and our AI Doctor CodyMd.
Cody, the AI Doctor
Hi there! You're here today to discuss feeling fatigued and low on energy, is that right?
Patient
Yes, that's correct.
Cody, the AI Doctor
Thanks for sharing that with me. I'm here to help identify what might be going on. Could you tell me when you first started noticing these symptoms?
Patient
It’s been ongoing for about a year now. It began gradually.
Cody, the AI Doctor
I see. When your fatigue started, did you notice if it was associated with any specific events or changes in your life?
Patient
Not really. It just crept up on me without any apparent reason.
Cody, the AI Doctor
Got it. Have you experienced any other symptoms alongside the fatigue, like changes in mood or sleeping patterns?
Patient
Well, I've definitely been feeling more anxious than usual, and I’ve been having trouble sleeping. I’m always moving my legs at night and it keeps me awake.
Cody, the AI Doctor
How about your motivation or interest in activities you typically enjoy?
Patient
Sometimes I just don’t feel like doing anything. It’s like I lose interest and motivation, and I feel kind of sad.
Cody, the AI Doctor
I'm sorry to hear that. Do you also experience any physical sensations like feeling cold more often than usual?
Patient
Yeah, sometimes I feel cold and clammy, even when it doesn’t seem that cold.
Cody, the AI Doctor
Understood. Let's talk about your health habits. Are there any routines or dietary habits you think might be affecting your energy levels?
Patient
My diet could definitely be better. I’m really busy at work, so I don’t eat a lot of fruits and vegetables.
Cody, the AI Doctor
Okay, thank you for letting me know. Just to understand your health history better, do you have any other medical conditions or take any medications regularly?
Patient
No, I don’t have any other conditions, and I’m not on any medications.
Cody, the AI Doctor
All right. Can I ask about your menstrual cycle? Are your periods regular, and how long do they usually last?
Patient
They’re pretty regular, but my periods are heavy and last about a week or more.
Cody, the AI Doctor
Thank you for sharing that. Heavy menstrual bleeding can sometimes contribute to certain health conditions. I am going to process this information to offer you the best assessment.
Based on the information and conversations with Cody, we have prepared a top 3 AI Diagnosis List.
1. Iron Deficiency Anemia( 55 % probability)
Often caused by heavy menstrual bleeding, leading to decreased energy levels, feeling cold, pale or clammy skin, and restless legs.
2. Depression(25 % probability)
Can explain low energy, loss of interest, anxiety, and sleep disturbances. However, no significant personal or family history suggests depression prominently.
3. Hypothyroidism(20 % probability)
May cause fatigue and feeling cold, but less supported due to the lack of other symptoms like weight gain or significant changes in hair or skin.

Dr. Albert DiPiero
The patient's persistent fatigue and associated symptoms such as restless legs demand a thorough evaluation. CodyMD's AI technology plays a vital role in synthesizing symptoms and providing an initial set of probable diagnoses. Here is my further analysis:
1. Iron Deficiency Anemia (IDA)(65% probability)
Given the heavy menstrual bleeding and the presence of restless legs, which can be indicative of IDA, this diagnosis is notably plausible. While the AI’s analysis highlights this condition, clinical evaluation and serum iron tests would confirm IDA, considering the symptom match.
2. Depression(25% probability)
The lack of a significant depressive history makes this a secondary consideration. Restless sleep and loss of motivation partially corroborate this diagnosis, but further psychological evaluation would clarify its relevance.
3. Hypothyroidism(10% probability)
The likelihood of this condition is diminished due to the absence of key symptoms like weight gain or skin changes. Nonetheless, thyroid function tests should remain part of the differential to rule this out definitively.
4. Other Considerations
Conditions such as Chronic Fatigue Syndrome align with prolonged, unexplained fatigue, although less corroborated by specific indicators.
Next Steps for Evaluation
Diagnostic Testing:
Serum Iron and Ferritin Levels and TIBC: Essential for assessing iron deficiency, the most specific indicator being a serum ferritin level <14 ng/mL.
Hemoglobin Electrophoresis: In cases where iron studies remain normal, to explore other anemia types.
Endoscopy: Indicated in non-menstruating patients for identifying potential gastrointestinal bleeding sources should iron deficiency be established.
Potential Treatment Modalities
Iron Supplementation:
Oral Iron Therapy: Prescribing iron sulfate daily or every other day for six months is the primary course, correcting deficiencies linked to IDA.
Parenteral Iron: For patients unable to digest oral supplements or those undergoing dialysis, parenteral methods offer an alternative solution.
Non-medication Interventions:
Dietary Adjustments: Emphasizing iron-rich foods in diet to bolster stores naturally.
Sleep Hygiene and Behavioral Therapy: Assisting with anxiety and sleep disturbances, potentially alleviating restless legs syndrome.
Counseling or Psychological Support: If depression remains a consideration, structured therapies may offer significant improvements.
Transfusion Needs:
Severe Anemia Intervention: In cases of critical anemia with severe symptoms, a blood transfusion may be necessary to stabilize the patient quickly.
Conclusion
Integrating AI assessments with clinical expertise presents a robust framework for accurate diagnosis and patient-focused care. By systematically addressing the most likely conditions and employing a combination of diagnostic evaluations and effective treatments, we can significantly enhance patient outcomes. The balance of AI and human assessment enriches this process, affording individuals the benefits of swift and comprehensive care interventions.
CodyMD is a very precise and accessible app. My consultation with CodymMD is commendable and I highly recommend it for others to try CodyMD especially for assessment and consultation purposes.
TrustPilot Review
Dr Cody spot on, better than most Human Drs. Also far more pleasant. Try him, he could better help you understand your issues. He will give you good info for your Drs visit as well.
TrustPilot Review
It gave me the best response possible and suggested simple self care treatment options which I'm in favor with. It has a to the point interface and brief answer for better understanding.
TrustPilot Review
Table of Contents
Common Questions
Chat with CodyMD
Cody's Chat with Patient
Cody's AI Summary
Top 3 AI Diagnosis List
Review by Dr Albert DiPiero
Dr. DiPiero Video Guide to this Case Study
Resource Center
Testimonials
Share this Case Study
Meet your host

Albert DiPiero, MD MPH FACP
I am a co-founder and the Chief Medical Officer at CodyMD and your host for this edition of Cody Grand Rounds. I have been a practicing physician and faculty member at medical schools for over 26 years.
About The AI Doctor Case Study
CodyMD is a partnership between Human Doctors and AI Doctors. Cody is an AI Doctor who helps thousands of people every day. At each Cody Grand Rounds, I select a real case and review it with Cody, the AI Doctor.
Each case is based on a real patient but has been modified to maintain privacy and to emphasize certain teaching points.
What causes fatigue and low energy?
How does anxiety affect sleep?
What are symptoms of iron deficiency anemia (IDA)?
How can diet impact energy levels?
What is hypothyroidism?
How do heavy periods affect health?
What steps can be taken to improve fatigue?
Can AI doctors diagnose the causes of fatigue and low energy?
What is the role of AI symptom checker?
Click the button below to initiate a conversation with CodyMD, your AI Doctor.
Below is a conversation transcript between the patient and our AI Doctor CodyMd.
Cody, the AI Doctor
Hi there! You're here today to discuss feeling fatigued and low on energy, is that right?
Patient
Yes, that's correct.
Cody, the AI Doctor
Thanks for sharing that with me. I'm here to help identify what might be going on. Could you tell me when you first started noticing these symptoms?
Patient
It’s been ongoing for about a year now. It began gradually.
Cody, the AI Doctor
I see. When your fatigue started, did you notice if it was associated with any specific events or changes in your life?
Patient
Not really. It just crept up on me without any apparent reason.
Cody, the AI Doctor
Got it. Have you experienced any other symptoms alongside the fatigue, like changes in mood or sleeping patterns?
Patient
Well, I've definitely been feeling more anxious than usual, and I’ve been having trouble sleeping. I’m always moving my legs at night and it keeps me awake.
Cody, the AI Doctor
How about your motivation or interest in activities you typically enjoy?
Patient
Sometimes I just don’t feel like doing anything. It’s like I lose interest and motivation, and I feel kind of sad.
Cody, the AI Doctor
I'm sorry to hear that. Do you also experience any physical sensations like feeling cold more often than usual?
Patient
Yeah, sometimes I feel cold and clammy, even when it doesn’t seem that cold.
Cody, the AI Doctor
Understood. Let's talk about your health habits. Are there any routines or dietary habits you think might be affecting your energy levels?
Patient
My diet could definitely be better. I’m really busy at work, so I don’t eat a lot of fruits and vegetables.
Cody, the AI Doctor
Okay, thank you for letting me know. Just to understand your health history better, do you have any other medical conditions or take any medications regularly?
Patient
No, I don’t have any other conditions, and I’m not on any medications.
Cody, the AI Doctor
All right. Can I ask about your menstrual cycle? Are your periods regular, and how long do they usually last?
Patient
They’re pretty regular, but my periods are heavy and last about a week or more.
Cody, the AI Doctor
Thank you for sharing that. Heavy menstrual bleeding can sometimes contribute to certain health conditions. I am going to process this information to offer you the best assessment.
Based on the information and conversations with Cody, we have prepared a top 3 AI Diagnosis List.
1. Iron Deficiency Anemia( 55 % probability)
Often caused by heavy menstrual bleeding, leading to decreased energy levels, feeling cold, pale or clammy skin, and restless legs.
2. Depression(25 % probability)
Can explain low energy, loss of interest, anxiety, and sleep disturbances. However, no significant personal or family history suggests depression prominently.
3. Hypothyroidism(20 % probability)
May cause fatigue and feeling cold, but less supported due to the lack of other symptoms like weight gain or significant changes in hair or skin.

Dr. Albert DiPiero
The patient's persistent fatigue and associated symptoms such as restless legs demand a thorough evaluation. CodyMD's AI technology plays a vital role in synthesizing symptoms and providing an initial set of probable diagnoses. Here is my further analysis:
1. Iron Deficiency Anemia (IDA)(65% probability)
Given the heavy menstrual bleeding and the presence of restless legs, which can be indicative of IDA, this diagnosis is notably plausible. While the AI’s analysis highlights this condition, clinical evaluation and serum iron tests would confirm IDA, considering the symptom match.
2. Depression(25% probability)
The lack of a significant depressive history makes this a secondary consideration. Restless sleep and loss of motivation partially corroborate this diagnosis, but further psychological evaluation would clarify its relevance.
3. Hypothyroidism(10% probability)
The likelihood of this condition is diminished due to the absence of key symptoms like weight gain or skin changes. Nonetheless, thyroid function tests should remain part of the differential to rule this out definitively.
4. Other Considerations
Conditions such as Chronic Fatigue Syndrome align with prolonged, unexplained fatigue, although less corroborated by specific indicators.
Next Steps for Evaluation
Diagnostic Testing:
Serum Iron and Ferritin Levels and TIBC: Essential for assessing iron deficiency, the most specific indicator being a serum ferritin level <14 ng/mL.
Hemoglobin Electrophoresis: In cases where iron studies remain normal, to explore other anemia types.
Endoscopy: Indicated in non-menstruating patients for identifying potential gastrointestinal bleeding sources should iron deficiency be established.
Potential Treatment Modalities
Iron Supplementation:
Oral Iron Therapy: Prescribing iron sulfate daily or every other day for six months is the primary course, correcting deficiencies linked to IDA.
Parenteral Iron: For patients unable to digest oral supplements or those undergoing dialysis, parenteral methods offer an alternative solution.
Non-medication Interventions:
Dietary Adjustments: Emphasizing iron-rich foods in diet to bolster stores naturally.
Sleep Hygiene and Behavioral Therapy: Assisting with anxiety and sleep disturbances, potentially alleviating restless legs syndrome.
Counseling or Psychological Support: If depression remains a consideration, structured therapies may offer significant improvements.
Transfusion Needs:
Severe Anemia Intervention: In cases of critical anemia with severe symptoms, a blood transfusion may be necessary to stabilize the patient quickly.
Conclusion
Integrating AI assessments with clinical expertise presents a robust framework for accurate diagnosis and patient-focused care. By systematically addressing the most likely conditions and employing a combination of diagnostic evaluations and effective treatments, we can significantly enhance patient outcomes. The balance of AI and human assessment enriches this process, affording individuals the benefits of swift and comprehensive care interventions.
CodyMD is a very precise and accessible app. My consultation with CodymMD is commendable and I highly recommend it for others to try CodyMD especially for assessment and consultation purposes.
TrustPilot Review
Dr Cody spot on, better than most Human Drs. Also far more pleasant. Try him, he could better help you understand your issues. He will give you good info for your Drs visit as well.
TrustPilot Review
It gave me the best response possible and suggested simple self care treatment options which I'm in favor with. It has a to the point interface and brief answer for better understanding.
TrustPilot Review